An effective chemoselective esterification of hydroxybenzoic acids in ionic liquid promoted by KF

被引：8

作者：

Biondini, D ^{[1
]}

Brinchi, L ^{[1
]}

Germani, R ^{[1
]}

Savelli, G ^{[1
]}

机构：

[1] Univ Perugia, Dipartimento Chim, Ctr Eccellenza Mat Innovat Nanostrutt, I-06123 Perugia, Italy

来源：

LETTERS IN ORGANIC CHEMISTRY | 2006年 / 3卷 / 03期

关键词：

ionic liquids; potassium fluoride; esterification; hydroxybenzoic acids; nucleophilic substitution;

D O I：

10.2174/157017806775789813

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ionic liquid based on the 1,3-diinethylimidazolium methanesulfonate has been used as efficient medium for the chcrnoselective synthesis of benzylic, allylic and phenacylic esters of hydroxybenzoic acids using KF as promoting base.

引用

页码：207 / 211

页数：5

共 29 条

[1]

BOSMANN A, 2003, Patent No. 03037835

[2] Ionic liquids as reaction media for esterification of carboxylate sodium salts with alkyl halides [J].

Brinchi, L ;

Germani, R ;

Savelli, G .

TETRAHEDRON LETTERS, 2003, 44 (10) :2027-2029

[3] Efficient esteritication of carboxylic acids with alkyl halides catalyzed by fluoride ions in ionic liquids [J].

Brinchi, L ;

Germani, R ;

Savelli, G .

TETRAHEDRON LETTERS, 2003, 44 (35) :6583-6585

[4] FLUORIDE-ION AS A BASE IN ORGANIC-SYNTHESIS [J].

CLARK, JH .

CHEMICAL REVIEWS, 1980, 80 (05) :429-452

[5]

CLARK JH, 1977, TETRAHEDRON LETT, V18, P599

[6]

DESMURS JR, 1992, Patent No. 467727

[7] Ionic liquid (molten salt) phase organometallic catalysis [J].

Dupont, J ;

de Souza, RF ;

Suarez, PAZ .

CHEMICAL REVIEWS, 2002, 102 (10) :3667-3691

[8]

Greene T. W., 1999, PROTECTIVE GROUPS OR, P369

[9]

GRUNDY J, 1972, TETRAHEDRON LETT, V13, P757

[10] A simple and effective method for chemoselective esterification of phenolic acids [J].

Guo, W ;

Li, JF ;

Fan, NJ ;

Wu, WW ;

Zhou, PW ;

Xia, CZ .

SYNTHETIC COMMUNICATIONS, 2005, 35 (01) :145-152

← 1 2 3 →