Genetic variability within Trypanosoma brucei gambiense:: evidence for the circulation of different genotypes in human African trypanosomiasis patients in Cote d'ivoire

被引：24

作者：

Truc, P

Ravel, S

Jamonneau, V

N'Guessan, P

Cuny, G

机构：

[1] Inst Rech Dev, Dept Soc & Sante, Lab Rech & Coordinat Trypanosomoses, UR 035, F-34398 Montpellier 5, France

[2] Inst Pierre Richet, Bouake, Cote Ivoire

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2002年 / 96卷 / 01期

关键词：

trypanosomiasis; Trypanosoma brucei gambiense; genotypes; mixed infection; microsatellites; genetic variability; Cote d'Ivoire;

D O I：

10.1016/S0035-9203(02)90237-3

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

For 23 Ivoirian patients infected by Trypanosoma brucei gambiense, isolation and genetic characterization using PCR and microsatellite primers were performed (in 1996-99) using 2 different isolates (A and 13) from each patient. When using TBDAC 1/2, 7 genotypes were observed, and DNAs A and B for 2 patients were different. This might be the first evidence of the presence of 2 different genotypes of T. b. gambiense group I in the same patient.

引用

页码：52 / 55

页数：4

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