Long-term Results of Treatment with Nucleoside and Nucleotide Analogues (Entecavir and Tenofovir) for Chronic Hepatitis B

被引：21

作者：

Asselah, Tarik ^{[1
,2
]}

Marcellin, Patrick ^{[1
,2
]}

机构：

[1] INSERM, U773, CRB3, F-75654 Paris 13, France

[2] Univ Paris Diderot, Hop Beaujon, AP HP, Dept Hepatol,Serv Hepatol, F-92110 Clichy, France

来源：

CLINICS IN LIVER DISEASE | 2013年 / 17卷 / 03期

关键词：

Personalized medicine; PEG-IFN; Analogues; Cirrhosis; Fibrosis regression; DISOPROXIL FUMARATE; PEGINTERFERON ALPHA-2A; HBEAG SEROCONVERSION; VIRUS INFECTION; LAMIVUDINE; COMBINATION; THERAPY; DNA;

D O I：

10.1016/j.cld.2013.05.001

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Chronic hepatitis B virus (HBV) infection, affecting approximately 350 to 400 million people worldwide, is associated with significant morbidity and mortality. Chronic hepatitis B remains a public health issue despite marked progress in public intervention programs. Individuals with chronic HBV infection have an increased risk for cirrhosis, decompensated liver disease, and hepatocellular carcinoma. The availability of safe and effective vaccines has reduced the burden of diseases. The choice of appropriate pharmacotherapy is critical in altering the course of the infection and reducing the costs associated with the management of chronic hepatitis B.

引用

页码：445 / +

页数：7

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