Folate intake in young women and their knowledge of preconceptional folate supplementation to prevent neural tube defects

被引:14
作者
Wild, J [1 ]
Schorah, CJ [1 ]
Maude, K [1 ]
Levene, MI [1 ]
机构
[1] UNIV LEEDS,SCH MED,CTR REPROD GROWTH & DEV,LEEDS LS2 9JT,W YORKSHIRE,ENGLAND
来源
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1996年 / 70卷 / 02期
关键词
dietary folate; folic acid supplementation; neural tube defect;
D O I
10.1016/S0301-2115(95)02584-7
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives: To ascertain knowledge of periconceptional folate for prevention of neural tube defect (NTD) and to estimate folate intake in young women. Study design: Three hundred young women were questioned about their knowledge of folate for prevention of NTD. Their folate intake was assessed by food frequency questionnaire. Results: Fourteen per cent of 16-19 year olds and 41% of undergraduates were aware of the need to increase folate intake before conception. Median folate intake was estimated to be 235 mu g/d in 16-19 year olds and 248.5 mu g/d in undergraduates. More than a quarter of women in both groups had folate intakes less than the reference nutrient intake (RNI) (200 mu g/d) below which prevalence of NTD rises dramatically and these women would therefore be at increased risk of having a child with NTD should they have an unplanned pregnancy. Conclusions: Strategies are required to increase folate intake among young women and inform them of the benefit of peri-conceptional folate supplementation. Copyright (C) 1996 Elsevier Science Ireland Ltd.
引用
收藏
页码:185 / 189
页数:5
相关论文
共 21 条
[1]   MINIMAL COMPLIANCE WITH THE DEPARTMENT-OF-HEALTH RECOMMENDATION FOR ROUTINE FOLATE PROPHYLAXIS TO PREVENT FETAL NEURAL-TUBE DEFECTS [J].
CLARK, NAC ;
FISK, NM .
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1994, 101 (08) :709-710
[2]   Effect of increasing dietary folate on red-cell folate: Implications for prevention of neural tube defects [J].
Cuskelly, GJ ;
McNulty, H ;
Scott, JM .
LANCET, 1996, 347 (9002) :657-659
[3]   PREVENTION OF CONGENITAL-ABNORMALITIES BY PERICONCEPTIONAL MULTIVITAMIN SUPPLEMENTATION [J].
CZEIZEL, AE .
BRITISH MEDICAL JOURNAL, 1993, 306 (6893) :1645-1648
[4]  
*DEP HLTH, 1992, FOL AC PREV NEUR TUB, P25
[5]   CHANGES IN THE DIETS OF UNIVERSITY-STUDENTS OVER A 6-YEAR PERIOD (1986-1991) [J].
EVES, A ;
KIPPS, M ;
PARLETT, G .
JOURNAL OF HUMAN NUTRITION AND DIETETICS, 1994, 7 (05) :363-376
[6]  
*HLTH ED AUTH, 1996, AW ATT BEH FOL AC WO
[7]  
Holland B., 1991, MCCANCE WIDDOWSONS C, V5th
[8]  
Motulsky AG, 1996, AM J HUM GENET, V58, P17
[9]  
*MRC VIT STUD RES, 1991, LANCET, V338, P131
[10]  
NELSONPIERCY C, 1995, BRIT J OBSTET GYNAEC, V102, P171, DOI 10.1111/j.1471-0528.1995.tb09080.x