Role of Mycoplasma pneumoniae in pediatric encephalitis

被引：26

作者：

Domenech, C. ^{[1
]}

Leveque, N. ^{[2
]}

Lina, B. ^{[2
]}

Najioullah, F. ^{[2
]}

Floret, D. ^{[1
]}

机构：

[1] Univ Lyon 1, Hosp Civils Lyon, Hop Edouard Herriot, F-69365 Lyon, France

[2] Univ Lyon 1, Hosp Civils Lyon, Lab Virol Est, F-69365 Lyon, France

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2009年 / 28卷 / 01期

关键词：

POLYMERASE CHAIN-REACTION; NERVOUS-SYSTEM COMPLICATIONS; ACUTE CHILDHOOD ENCEPHALITIS; CEREBROSPINAL-FLUID; INFECTION; DIAGNOSIS; MULTICENTER; CHILDREN; ASSAY; DNA;

D O I：

10.1007/s10096-008-0591-6

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A retrospective study investigating all the infectious encephalitis cases hospitalized at the pediatric intensive care unit of Edouard Herriot University Hospital in Lyon, France, was carried out in order to estimate the prevalence of Mycoplasma pneumoniae in acute childhood encephalitis. From January 2001 to December 2005, the cases of 29 children were selected and reviewed. M. pneumoniae related encephalitis was considered as probable in five cases (17%) on the basis of positive serological tests or positive polymerase chain reaction (PCR) tests in throat or nasopharyngeal swab while the PCR tests performed from the cerebrospinal fluid were negative. This study suggests that M. pneumoniae may be a major cause of infectious encephalitis in children as well as enteroviruses or Epstein-Barr virus detected in five and three cases, respectively.

引用

页码：91 / 94

页数：4

共 20 条

[1] DETECTION OF MYCOPLASMA-PNEUMONIAE BY USING THE POLYMERASE CHAIN-REACTION [J].

BERNET, C ;

GARRET, M ;

DEBARBEYRAC, B ;

BEBEAR, C ;

BONNET, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 1989, 27 (11) :2492-2496

[2] Acute childhood encephalitis and Mycoplasma pneumoniae [J].

Bitnun, A ;

Ford-Jones, EL ;

Petric, M ;

MacGregor, D ;

Heurter, H ;

Nelson, S ;

Johnson, G ;

Richardson, S .

CLINICAL INFECTIOUS DISEASES, 2001, 32 (12) :1674-1684

[3]

Bitnun Ari, 2003, Semin Pediatr Infect Dis, V14, P96, DOI 10.1053/spid.2003.127226

[4] Pediatric encephalitis:: What is the role of Mycoplasma pneumoniae? [J].

Christie, Laura J. ;

Honarmand, Somayeh ;

Talkington, Deborah F. ;

Gavali, Shilpa S. ;

Preas, Chris ;

Pan, Chao-Yang ;

Yagi, Shigeo ;

Glaser, Carol A. .

PEDIATRICS, 2007, 120 (02) :305-313

[5] Diagnosis, treatment, and prognosis of Mycoplasma pneumoniae childhood encephalitis:: Systematic review of 58 cases [J].

Daxboeck, F ;

Blacky, A ;

Seidl, R ;

Krause, R ;

Assadian, O .

JOURNAL OF CHILD NEUROLOGY, 2004, 19 (11) :865-871

[6] Mycoplasma pneumoniae central nervous system infections [J].

Daxboeck, Florian .

CURRENT OPINION IN NEUROLOGY, 2006, 19 (04) :374-378

[7] Detection and variant identification of HHV-6 by a non-radioactive hybridization microplate assay for amplimers detection [J].

Gautheret, A ;

Aubin, JT ;

Poirel, L ;

Chopineau, S ;

Agut, H ;

Dussaix, E .

JOURNAL OF VIROLOGICAL METHODS, 1996, 58 (1-2) :33-40

[8] Beyond viruses: Clinical profiles and etiologies associated with encephalitis [J].

Glaser, C. A. ;

Honarmand, S. ;

Anderson, L. J. ;

Schnurr, D. P. ;

Forghani, B. ;

Cossen, C. K. ;

Schuster, F. L. ;

Christie, L. J. ;

Tureen, J. H. .

CLINICAL INFECTIOUS DISEASES, 2006, 43 (12) :1565-1577

[9] Mycoplasma pneumoniae and central nervous system complications:: A review. [J].

Guleria, R ;

Nisar, N ;

Chawla, TC ;

Biswas, NR .

JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 2005, 146 (02) :55-63

[10] Etiology of acute childhood encephalitis at The Hospital for Sick Children, Toronto, 1994-1995 [J].

Kolski, H ;

Ford-Jones, EL ;

Richardson, S ;

Petric, M ;

Nelson, S ;

Jamieson, F ;

Blaser, S ;

Gold, R ;

Otsubo, H ;

Heurter, H ;

MacGregor, D .

CLINICAL INFECTIOUS DISEASES, 1998, 26 (02) :398-409

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