The use of 4-hetaryliden- and 4-aryliden-5(4H)-oxazolones as dienophiles. Appropriate reagents for the synthesis of cyclic analogues of natural amino acids

被引：23

作者：

Avenoza, A ^{[1
]}

Busto, JH ^{[1
]}

Paris, M ^{[1
]}

Peregrina, JM ^{[1
]}

Cativiela, C ^{[1
]}

机构：

[1] UNIV ZARAGOZA,CSIC,INST CIENCIA MAT ARAGON,DEPT ORGAN CHEM,ZARAGOZA 50009,SPAIN

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 04期

关键词：

D O I：

10.1002/jhet.5570340402

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This report describes the behavior of 4-hetaryliden- and 4-aryliden-5(4H)-oxazolones as dienophiles in the Diels-Alder reaction with several dienes. The application of this reaction to the synthesis of different conformationally constrained cyclic analogues of natural amino acids of pharmacological interest is also described.

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页码：1099 / 1110

页数：12

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