Surface imaging by self-propelled nanoscale probes

被引：77

作者：

Hess, H

Clemmens, J

Howard, J

Vogel, V

机构：

[1] Univ Washington, Dept Bioengn, Seattle, WA 98195 USA

[2] Univ Washington, Dept Physiol & Biophys, Seattle, WA 98195 USA

来源：

NANO LETTERS | 2002年 / 2卷 / 02期

关键词：

D O I：

10.1021/nl015647b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new approach to image microscopic surface properties is introduced. Information about surface properties such as topography is obtained by repeated acquisition of an optical signal from a large number of microscopic, self-propelled probes moving on random paths across a surface, These self-propelled probes sample the surface in a statistical process in contrast to the deterministic, linear sampling performed by a scanning probe microscope. This method is experimentally demonstrated using microtubules as probes, which are moved by the motor protein kinesin.

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页码：113 / 116

页数：4

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