Tick-borne encephalitis virus in Lithuania

被引：19

作者：

Mickiené, A

Vene, S

Golovljova, I

Laiskonis, A

Lindquist, L

Plyusnin, A

Lundkvist, Å ^{[1
]}

机构：

[1] Swedish Inst Infect Dis Control, S-17182 Stockholm, Sweden

[2] Karolinska Inst, Ctr Microbiol & Tumor Biol, Stockholm, Sweden

[3] Karolinska Inst, Huddinge Hosp, Dept Infect Dis, S-10401 Stockholm, Sweden

[4] Kaunas Med Univ, Clin Infect Dis, Kaunas, Lithuania

[5] Swedish Inst Infect Dis Control, Stockholm, Sweden

[6] Karolinska Inst, Ctr Microbiol & Tumor Biol, Stockholm, Sweden

[7] Inst Clin & Expt Med, Tallinn, Estonia

[8] Univ Helsinki, Haartman Inst, Dept Virol, Helsinki, Finland

[9] Swedish Inst Infect Dis Control, Stockholm, Sweden

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 2001年 / 20卷 / 12期

关键词：

Ixodes Ricinus; Infectious Disease Control; TBEV Strain; TBEV Infection; Viremic Phase;

D O I：

10.1007/s10096-001-0637-5

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Tick-borne encephalitis (TBE) is a severe problem in Lithuania, indicated by the 171 to 645 serologically confirmed cases that occurred each year between 1993 and 1999. In the present report, the first isolation and partial genetic analysis of a Lithuanian TBE virus (TBEV) strain isolated from a patient's serum sample is described. The patient was bitten by a tick while visiting the Lazdijai district (Veisiejai forest) in the southernmost part of Lithuania, a geographical area where Ixodes ricinus but not Ixodes persulcatus ticks are known to be present. The E protein-encoding viral gene sequence (nt 74-1273) recovered from the TBEV isolate showed the closest similarity to previously characterized European strains of the Western TBEV subtype, including the prototype TBEV strain Neudoerfl and those from neighbouring Latvia. Accordingly, the Lithuanian isolate was placed within the Western genetic lineage of TBEV in phylogenetic trees.

引用

页码：886 / 888

页数：3

共 15 条

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