Different Locomotor Activities and Monoamine Levels in the Brains of Djungarian Hamsters (D-sungorus) and Roborovskii Hamsters (D-roborovskii)

被引：10

作者：

Kabuki, Yusuke ^{[1
]}

Yamane, Haruka ^{[1
]}

Hamasu, Kousuke ^{[1
]}

Furuse, Mitsuhiro ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Bioresource & Bioenvironm Sci, Lab Adv Anim & Marine Bioresources, Fukuoka 8128581, Japan

来源：

EXPERIMENTAL ANIMALS | 2008年 / 57卷 / 05期

关键词：

Djungarian hamster; locomotor activity; monoamine; open field; Roborovskii hamster;

D O I：

10.1538/expanim.57.447

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Two species of the genus Phodopus, Djungarian hamster (P. sungorus) and Roborovskii hamster (P. roborovskii), differ in their behavior The Roborovskii hamster has high locomotor activity (hyperactivity) compared to the Djungarian hamster. In this study, we compared locomotor activity of the hamsters in different environments, and compared their brain monoamine and metabolite levels to identify the mechanism by which both hamsters move differently. Activity of Roborovskii hamsters was significantly higher than Djungarian hamsters in the open field, while no difference was observed in their home cage. Dopamine (DA) and serotonin (5-HT) levels in the whole brain of Roborovskii hamster were significantly lower and their metabolic turnover rates were significantly higher than those of the Djungarian hamster. We conclude that the difference in activity under the novel environment between both species is partly, but not entirely, explained by the difference in monoamine levels and their metabolism in the brain.

引用

页码：447 / 452

页数：6

共 18 条

[1] Elevated serotonin is involved in hyperactivity but not in the paradoxical effect of amphetamine in mice neonatally lesioned with 6-hydroxydopamine [J].