Function and regulation of Rnd proteins

被引：171

作者：

Chardin, P ^{[1
]}

机构：

[1] CNRS, Inst Pharmacol Mol & Cellulaire, F-06560 Valbonne, France

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2006年 / 7卷 / 01期

关键词：

D O I：

10.1038/nrm1788

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

The Rnd proteins, which form a distinct sub-group of the Rho family of small GTP-binding proteins, have been shown to regulate the organization of the actin cytoskeleton in several tissues. In the brain, they participate in neurite extension, whereas in smooth muscle, they modulate contractility. Recent evidence has shown that Rnd3 (RhoE) is also involved in the regulation of cell-cycle progression and transformation, indicating that these proteins might have other, as yet unexplored roles.

引用

页码：54 / 62

页数：9

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