N-halamine/quat siloxane copolymers for use in biocidal coatings

被引:132
作者
Liang, J
Chen, Y
Barnes, K
Wu, R
Worley, SD [1 ]
Huang, TS
机构
[1] Auburn Univ, Dept Chem, Auburn, AL 36849 USA
[2] Auburn Univ, Dept Nutr & Food Sci, Auburn, AL 36849 USA
关键词
bacteria; bioactivity; siloxane;
D O I
10.1016/j.biomaterials.2005.11.020
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A series of copolymers incorporating N-halamine siloxane and quaternary ammonium salt siloxane units has been prepared. The primary function of the quat units was to render the siloxane copolymers soluble in water. The copolymers have been coated onto cotton swatches and evaluated for biocidal efficacy against Staphlylococcus aureus and Escherichia coli O157:H7. It was determined that both N-halamine and quat functional groups were effective against S. aureus, but only the N-halamine units were effective against Escherichia coli O157:H7. The copolymers should be useful for applications for which aqueous media is preferred over organic solvents to be used during coating procedures. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2495 / 2501
页数:7
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