A convenient and selective synthesis of unsymmetrical benzoins via the cyanide ion catalyzed cleavage of benzils

被引：33

作者：

Demir, AS ^{[1
]}

Reis, Ö ^{[1
]}

机构：

[1] Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey

来源：

TETRAHEDRON | 2004年 / 60卷 / 17期

关键词：

benzoin; benzil; unsymmetrical; photolabile;

D O I：

10.1016/j.tet.2004.03.016

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cyanide ion-catalyzed cleavage of benzils is used for the generation of various 'masked' acyl intermediates. The reaction of these intermediates with various aldehydes furnishes the corresponding esters Of unsymmetrical benzoins in very good yields. A variety of unsymmetrical benzoin derivatives are synthesized in this way, including ferrocene derivatives. The hydrolysis of benzoin esters and their subsequent oxidation affords the corresponding unsymmetrical benzoins and benzils in high yield. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：3803 / 3811

页数：9

共 42 条

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