Triterpene trimers from Maytenus scutioides:: Cycloaddition compounds?

被引:27
作者
González, AG
Alvarenga, NL
Bazzocchi, IL [1 ]
Ravelo, AG
Moujir, L
机构
[1] Univ La Laguna, Inst Univ Bioorgan Antonio Gonzalez, La Laguna 38206, Tenerife, Spain
[2] Univ La Laguna, Dept Microbiol & Biol Cellar, La Laguna 38206, Tenerife, Spain
来源
JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 08期
关键词
D O I
10.1021/np9900728
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
Two novel trimers, triscutins A and B (1 and 2), based on pristimerin triterpene units, were isolated and characterized from Maytenus scutioides. Their structures were determined on the basis of spectroscopic evidence, including H-1-C-13 heteronuclear correlation (HMQC), long-range correlation with inverse detection (HMBC), and ROESY NMR experiments; and their absolute configurations, by means of CD studies. Compounds 1 and 2 were assayed for antimicrobial and cytotoxic activities, and their possible biosynthetic route is proposed.
引用
收藏
页码:1185 / 1187
页数:3
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