Changes in Hepatic Risk Factors, Metabolic Variables, Body Composition, and Physical Fitness in Obese Children After a One-Year Weight Loss Program

被引：4

作者：

Rohrer, Tilman R. ^{[1
]}

Rizzo, Vincenzo F. ^{[1
]}

Caesar, Jochen I. J. ^{[1
]}

Muelbredt, Oliver ^{[2
]}

Sprengart, Stephanie ^{[3
]}

Gortner, Ludwig ^{[1
]}

Stierkorb, Eva ^{[1
]}

机构：

[1] Saarland Univ Hosp, Dept Paediat & Neonatol, D-66421 Homburg, Germany

[2] Saarland Univ Hosp, Saarbrucken Olymp Training Ctr, D-66421 Homburg, Germany

[3] Saarland Univ Hosp, Physiotherapy Sch, D-66421 Homburg, Germany

来源：

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | 2008年 / 21卷 / 09期

关键词：

childhood obesity; liver disease risk factors; metabolic variables; physical exercise; weight loss program; insulin resistance;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Obesity can cause insulin resistance and cardiovascular and liver disease. The aim of this stud), was to analyze changes in laboratory values, body composition, and physical fitness before and after a one-year weight loss program with nutritional education, psychological care, and physical exercise. Twenty-two obese children (16 boys, 6 girls; median age 11.9 [range 7-15] years; BMI SDS +2.4 [1.6-3.1]) participated in the program. Outcome measures included liver enzymes, insulin resistance (HOMA), lipids, body composition, physical strength and endurance. All children had an inverse HOMA/body composition correlation; Group 1 (reduced BMI SIDS after one year) had lower triglycerides, liver enzymes and improved body composition and fitness (p < 0.05). Group 2 (unchanged or increased BMI SDS) had worse body composition and increased endurance and strength of trunk extension (p < 0.05). Weight loss reduced risk factors for liver disease and improved insulin sensitivity. Body composition proved useful as a non-invasive indicator for insulin sensitivity.

引用

页码：837 / 845

页数：9

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