Advances in diffusion MRI acquisition and processing in the Human Connectome Project

被引:647
作者
Sotiropoulos, Stamatios N. [1 ]
Jbabdi, Saad [1 ]
Xu, Junqian [2 ,3 ]
Andersson, Jesper L. [1 ]
Moeller, Steen [2 ]
Auerbach, Edward J. [2 ]
Glasser, Matthew F. [4 ]
Hernandez, Moises [1 ]
Sapiro, Guillermo [5 ]
Jenkinson, Mark [1 ]
Feinberg, David A. [6 ,7 ]
Yacoub, Essa [2 ]
Lenglet, Christophe [2 ]
Van Essen, David C. [4 ]
Ugurbil, Kamil [2 ]
Behrens, Timothy E. J. [1 ,8 ]
机构
[1] Univ Oxford, Ctr Funct Magnet Resonance Imaging Brain FMRIB, Oxford, England
[2] Univ Minnesota, Ctr Magnet Resonance Res, Minneapolis, MN USA
[3] Icahn Sch Med Mt Sinai, Translat & Mol Imaging Inst, New York, NY USA
[4] Washington Univ, Dept Anat & Neurobiol, St Louis, MO USA
[5] Duke Univ, Dept Elect & Comp Engn, Durham, NC USA
[6] Adv MRI Technol, Sebastopol, CA USA
[7] Univ Calif Berkeley, Berkeley, CA 94720 USA
[8] UCL, Wellcome Trust Ctr NeuroImaging, London, England
关键词
TENSOR IMAGING TRACTOGRAPHY; POSTMORTEM HUMAN BRAINS; ECHO-PLANAR IMAGES; OLD-WORLD MONKEY; SPIN-ECHO; SPHERICAL DECONVOLUTION; K-SPACE; RESOLUTION; RECONSTRUCTION; BALL;
D O I
10.1016/j.neuroimage.2013.05.057
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The Human Connectome Project (HCP) is a collaborative 5-year effort to map human brain connections and their variability in healthy adults. A consortium of HCP investigators will study a population of 1200 healthy adults using multiple imaging modalities, along with extensive behavioral and genetic data. In this overview, we focus on diffusion MRI (dMRI) and the structural connectivity aspect of the project. We present recent advances in acquisition and processing that allow us to obtain very high-quality in-vivo MRI data, whilst enabling scanning of a very large number of subjects. These advances result from 2 years of intensive efforts in optimising many aspects of data acquisition and processing during the piloting phase of the project. The data quality and methods described here are representative of the datasets and processing pipelines that will be made freely available to the community at quarterly intervals, beginning in 2013. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:125 / 143
页数:19
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