Treatment of Tendon and Muscle Using Platelet-Rich Plasma

被引:280
作者
Mishra, Allan [1 ]
Woodall, James, Jr. [2 ]
Vieira, Amy [1 ]
机构
[1] Stanford Univ, Med Ctr, Dept Orthoped Surg, Menlo Med Clin, Menlo Pk, CA 94025 USA
[2] Univ Mississippi, Med Ctr, Dept Orthoped Surg, Jackson, MS 39216 USA
关键词
Platelet-rich plasma; PRP; Growth factors; Tendon; Muscle; Tendonitis; GROWTH-FACTORS; BONE-FORMATION; LEUKOCYTE GEL; STEM-CELLS; IN-VITRO; MACROPHAGES; REPAIR; TENDINOPATHY; INJURY; EXPRESSION;
D O I
10.1016/j.csm.2008.08.007
中图分类号
G8 [体育];
学科分类号
040301 [体育人文社会学];
摘要
Tendon and muscle injuries are common in elite and weekend athletes. Treatment of these injuries in both groups is rapidly evolving. Sports medicine patients are demanding better and less invasive solutions for all types of musculoskeletal disorders. In this context, platelet-rich plasma (PRP) has emerged as a potential solution. PRP is a fraction of whole blood containing concentrated growth factors and proteins. These cytokines direct tissue healing through autocrine and paracrine effects. The number of basic science, animal, and human investigations of PRP for tendon and muscle injuries worldwide has risen sharply in recent years. These studies are helping clinicians better understand the mechanisms of PRP and are guiding novel treatment protocols. In this paper, the value of PRP as a treatment for acute or chronic tendon and muscle disorders is explored.
引用
收藏
页码:113 / +
页数:14
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