Pattern formation and traveling waves in myxobacteria: Theory and modeling

被引：116

作者：

Igoshin, OA

Mogilner, A

Welch, RD

Kaiser, D

Oster, G ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Mol & Cellular Biol, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept ESPM, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA

[4] Univ Calif Davis, Dept Math, Davis, CA 95616 USA

[5] Stanford Univ, Dept Biochem, Stanford, CA 94305 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2001年 / 98卷 / 26期

关键词：

D O I：

10.1073/pnas.221579598

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Recent experiments have provided new quantitative measurements of the rippling phenomenon in fields of developing myxobacteria cells. These measurements have enabled us to develop a mathematical model for the ripple phenomenon on the basis of the biochemistry of the C-signaling system, whereby individuals signal by direct cell contact. The model quantitatively reproduces all of the experimental observations and illustrates how intracellular dynamics, contact-mediated intercellular communication, and cell motility can coordinate to produce collective behavior. This pattern of waves is qualitatively different from that observed in other social organisms, especially Dictyostelium discoideum, which depend on diffusible morphogens.

引用

页码：14913 / 14918

页数：6

共 33 条

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