Mechanisms of angiogenesis

被引：4494

作者：

Risau, W

机构：

[1] Max-Planck-Institute for PCR, W.G. Kerckhoff Institute, Parkstrasse 1

来源：

NATURE | 1997年 / 386卷 / 6626期

关键词：

D O I：

10.1038/386671a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

After the developing embryo has formed a primary vascular plexus by a process termed vasculogenesis, further blood vessels are generated by both sprouting and non-sprouting angiogenesis, which are progressively pruned and remodelled into a functional adult circulatory system. Recent results, particularly from the study of mice lacking some of the signalling systems involved, have greatly improved our understanding of the molecular basis underlying these events, and may suggest new approaches for treating conditions such as cancer that depend on angiogenesis.

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页码：671 / 674

页数：4

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