Aseptic meningitis associated with rofecoxib

被引：27

作者：

Bonnel, RA

Villalba, ML

Karwoski, CB

Beitz, J

机构：

[1] US FDA, Ctr Drug Evaluat & Res, Off Postmkt Drug Risk Assessment, Rockville, MD 20857 USA

[2] US FDA, Ctr Drug Evaluat & Res, Div Antiinflammatory Analges & Ophthalm Drug Prod, Rockville, MD 20857 USA

来源：

ARCHIVES OF INTERNAL MEDICINE | 2002年 / 162卷 / 06期

关键词：

D O I：

10.1001/archinte.162.6.713

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rofecoxib is a nonsteroidal anti-inflammatory drug that is reported to act by selectively inhibiting cyclooxygenase-2. A review and analysis of reports sent to the Spontaneous Reporting System of the Food and Drug Administration, Rockville, Md, suggest that aseptic meningitis is associated with rofecoxib use. To our knowledge, there have been no published reports of aseptic meningitis occurring in association with rofecoxib use to date. We report 5 serious cases of aseptic meningitis associated with rofecoxib use.

引用

页码：713 / 715

页数：3

共 17 条

[1] IBUPROFEN-RELATED MENINGITIS IN MIXED CONNECTIVE-TISSUE DISEASE [J].