The Effect of Camellia sinensis on Wound Healing Potential in an Animal Model

被引：64

作者：

Hajiaghaalipour, Fatemeh ^{[1
]}

Kanthimathi, M. S. ^{[1
]}

Abdulla, Mahmood Ameen ^{[2
]}

Sanusi, Junedah ^{[3
]}

机构：

[1] Univ Malaya, Fac Med, Ctr Prote Res, Dept Mol Med, Kuala Lumpur 50603, Malaysia

[2] Univ Malaya, Fac Med, Dept Biomed Sci, Kuala Lumpur 50603, Malaysia

[3] Univ Malaya, Fac Med, Dept Anat, Neurosci Res Grp, Kuala Lumpur 50603, Malaysia

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2013年 / 2013卷

关键词：

GREEN TEA; LEAF EXTRACT; PURINE ALKALOIDS; WHITE TEA; CATECHINS; SKIN;

D O I：

10.1155/2013/386734

中图分类号：

R [医药、卫生];

学科分类号：

100218 [急诊医学];

摘要：

Camellia sinensis (tea) is reported to have health benefits, including the building of healthy skin. This study evaluated the effects of topical application of Camellia sinensis extract on the rate of wound closure and the histology of wound area. A uniform area of 2.00 cm in diameter was excised from the neck of adult male Sprague Dawley rats. The animals were topically treated with 0.2 mL of vehicle (CMC), Intrasite gel (positive control), or 200 and 400 mg/mL of extract. Wounds dressed with the extract and Intrasite gel healed significantly earlier than those with vehicle. Histological analysis of the wound area after 10 days showed that wounds dressed with the extract had less scar width when compared to the control. The tissue contained less inflammatory cells and more collagen and angiogenesis, compared to wounds dressed with vehicle. In this study, Camellia sinensis showed high potential in wound healing activity.

引用

页数：7

共 34 条

[1]

Exploring the wound healing activity of Arnebia densiflora (Nordm.) Ledeb. by in vivo models [J].