Nitroaromatic Actuation of Mitochondrial Bioelectrocatalysis for Self-Powered Explosive Sensors

被引:61
作者
Germain, Marguerite N. [1 ]
Arechederra, Robert L. [1 ]
Minteer, Shelley D. [1 ]
机构
[1] St Louis Univ, Dept Chem, St Louis, MO 63103 USA
基金
美国国家科学基金会;
关键词
D O I
10.1021/ja807250b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Oligomycin-inhibited mitochondria-modified electrodes were used to electrochemically sense the presence of nitroaromatics owing to the selective ability of nitroaromatics to decouple the inhibition of pyruvate metabolism by the mitochondria. These oligomycin inhibited mitochondria-modified electrodes were employed as the bioanode in a pyruvate/air biofuel cell. This sensing mechanism could be used as a traditional electrochemical sensor or as a self-powered sensor.
引用
收藏
页码:15272 / +
页数:3
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