Recombination Is Associated with an Outbreak of Novel Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Viruses in China

被引：81

作者：

Shi, Mang ^{[1
,2
]}

Holmes, Edward C. ^{[1
,2
,3
]}

Brar, Manreetpal Singh ^{[4
]}

Leung, Frederick Chi-Ching ^{[4
,5
]}

机构：

[1] Univ Sydney, Sch Biol Sci, Sydney Emerging Infect & Biosecur Inst, Sydney, NSW 2006, Australia

[2] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia

[3] NIH, Fogarty Int Ctr, Bethesda, MD 20892 USA

[4] Univ Hong Kong, Sch Biol Sci, Hong Kong, Hong Kong, Peoples R China

[5] Nanjing Agr Univ, Bioinformat Ctr, Nanjing, Jiangsu, Peoples R China

来源：

JOURNAL OF VIROLOGY | 2013年 / 87卷 / 19期

基金：

澳大利亚国家健康与医学研究理事会;

关键词：

D O I：

10.1128/JVI.01270-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In 2009 to 2010, there was a marked increase in the number of infections with highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) in China. Through phylogenetic analysis, we show that viruses from this outbreak originated from a single recombination event, illustrating the potential importance of this process for disease emergence.

引用

页码：10904 / 10907

页数：4

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