Genotyping of Chlamydia trachomatis from clinical specimens in Taiwan

被引：48

作者：

Hsu, MC

Tsai, PY

Chen, KT

Li, LH

Chiang, CC

Tsai, JJ

Ke, LY

Chen, HY

Li, SY ^{[1
]}

机构：

[1] Ctr Dis Control, Ctr Lab Res & Diagnost, Lab Bacteriol & Mycol, Taipei, Taiwan

[2] Natl Cheng Kung Univ, Coll Med, Dept Publ Hlth, Tainan 70101, Taiwan

[3] Taipei City Hosp, Branch Dis Control & Prevent, Taipei, Taiwan

[4] Kaohsiung Med Univ, Chung Ho Mem Hosp, Kaohsiung, Taiwan

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2006年 / 55卷 / 03期

关键词：

D O I：

10.1099/jmm.0.46262-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This study was conducted to determine the prevalence and distribution of Chlamydia trachomatis genotypes in Taiwan. Urine and enclocervical-swab samples were collected from two hospitals located in northern and southern Taiwan. The genotypes of a total of 145 samples positive for C. trachomatis were analysed by sequencing the omp1 gene and this was successful in 102 samples. Nine different C. trachomatis genotypes were identified. Genotype E was the most prevalent (22%), followed by D and Da (19%), F (16%), J (15%), K (11%), G (11%), H (6%) and Ba (2%). There was a geographical difference in the prevalence of genotype H (P < 0.018) between northern and southern Taiwan. Sequence mutation analysis by BLAST searching against GenBank reference sequences identified 12 genetic variants from a total of 102 omp1 gene sequences.

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收藏

页码：301 / 308

页数：8

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[1] Serotypes of Chlamydia trachomatis and risk for development of cervical squamous cell carcinoma [J].

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Saikku, P ;

Koskela, P ;

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Dillner, J ;

Ikäheimo, I ;

Jellum, E ;

Lehtinen, M ;

Lenner, P ;

Hakulinen, T ;

Närvänen, A ;

Pukkala, E ;

Thoresen, S ;

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Paavonen, J .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (01) :47-51

[2] Typing of Chlamydia trachomatis strains from urine samples by amplification and sequencing the major outer membrane protein gene (omp1) [J].

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Bhullar, V ;

Yanpaisarn, S ;

Chaisilwattana, P ;

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Black, CM .

SEXUALLY TRANSMITTED INFECTIONS, 2001, 77 (06) :419-422

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Sanders, JA ;

Chaturvedi, AK ;

Slavinsky, J ;

Clayton, JL ;

Dumestre, J ;

Hagensee, ME .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (09) :3155-3161

[4] The epidemiology of Chlamydia trachomatis within a sexually transmitted diseases core group [J].

Brunham, RC ;

Kimani, J ;

Bwayo, J ;

Maitha, G ;

Maclean, I ;

Yang, CL ;

Shen, CX ;

Roman, S ;

Nagelkerke, NJD ;

Cheang, M ;

Plummer, FA .

JOURNAL OF INFECTIOUS DISEASES, 1996, 173 (04) :950-956

[5] Chlamydia trachomatis omp1 genotypic diversity and concordance with sexual network [J].

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Jolly, AM ;

Wylie, JL .

JOURNAL OF INFECTIOUS DISEASES, 2003, 187 (02) :279-286

[6] Evaluation of serotyping using monoclonal antibodies and PCR-RFLP for Chlamydia trachomatis serotype identification [J].

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DEAN, D ;

OUDENS, E ;

BOLAN, G ;

PADIAN, N ;

SCHACHTER, J .

JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (04) :1013-1022

[8] Molecular and mutation trends analyses of omp1 alleles for serovar E of Chlamydia trachomatis - Implications for the immunopathogenesis of disease [J].

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Millman, K .

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[9] Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping [J].

Dean, D ;

Suchland, RJ ;

Stamm, WE .

JOURNAL OF INFECTIOUS DISEASES, 2000, 182 (03) :909-916

[10] Quantitative Chlamydia trachomatis cultures:: Correlation of chlamydial inclusion-forming units with serovar, age, sex, and race [J].

Eckert, LO ;

Suchland, RJ ;

Hawes, SE ;

Stamm, WE .

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