Polysaccharides-based nanoparticles as drug delivery systems

被引：1341

作者：

Liu, Zonghua ^{[1
]}

Jiao, Yanpeng ^{[1
]}

Wang, Yifei ^{[2
]}

Zhou, Changren ^{[1
]}

Zhang, Ziyong ^{[1
]}

机构：

[1] Jinan Univ, Dept Mat Sci & Engn, Guangzhou 510632, Guangdong, Peoples R China

[2] Jinan Univ, Biomed Res & Dev Ctr, Guangzhou 510632, Guangdong, Peoples R China

来源：

ADVANCED DRUG DELIVERY REVIEWS | 2008年 / 60卷 / 15期

关键词：

Polysaccharide; Nanoparticle; Drug delivery system;

D O I：

10.1016/j.addr.2008.09.001

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Natural polysaccharides, due to their outstanding merits, have received more and more attention in the field of drug delivery systems. In particular, polysaccharides seem to be the most promising materials in the preparation of nanometeric carriers. This review relates to the newest developments in the preparation of polysaccharides-based nanoparticles. In this review, four mechanisms are introduced to prepare polysaccharides-based nanoparticles, that is, covalent crosslinking, ionic crosslinking, polyelectrolyte complex, and the self-assembly of hydrophobically modified polysaccharides. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：1650 / 1662

页数：13

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