Thin-layer chromatographic separation of enantiomeric dansylamino acids using a macrocyclic antibiotic as a chiral selector

被引：50

作者：

Bhushan, R

Parshad, V

机构：

[1] Department of Chemistry, University of Roorkee

来源：

JOURNAL OF CHROMATOGRAPHY A | 1996年 / 736卷 / 1-2期

关键词：

chiral stationary phases; TLC; enantiomer separation; amino acids; antibiotics; erythromycin;

D O I：

10.1016/0021-9673(95)01330-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The enantiomeric resolution of ten dansyl-DL-amino acids was achieved on thin silica gel plates impregnated with a macrocyclic antibiotic, erythromycin, as the chiral selector. Different combinations of 0.5 M aqueous NaCl-MeCN-MeOH were found to be successful in resolving various dansyl-DL-amino acids. Spots were detected using a fixed dual-wavelength (254 nm) ultraviolet chamber.

引用

页码：235 / 238

页数：4

共 17 条

[1] MACROCYCLIC ANTIBIOTICS AS A NEW CLASS OF CHIRAL SELECTORS FOR LIQUID-CHROMATOGRAPHY [J].