Dually cationic and anionic pH/temperature-sensitive injectable hydrogels and potential application as a protein carrier

被引:37
作者
Cong Truc Huynh [1 ]
Minh Khanh Nguyen [1 ]
Lee, Doo Sung [1 ]
机构
[1] Sungkyunkwan Univ, Dept Polymer Sci & Engn, Theranost Macromol Res Ctr, Suwon 440746, Gyeonggi Do, South Korea
基金
新加坡国家研究基金会;
关键词
SOL-GEL TRANSITION; BLOCK-COPOLYMER; TRIBLOCK COPOLYMER; CONTROLLED-RELEASE; PH; INSULIN;
D O I
10.1039/c2cc36134e
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Novel copolymers containing both anionic and cationic pH-sensitive moieties were reported. These amphoteric copolymers exhibited special closed-loop reversible sol-gel-sol phase transitions in response to both pH and temperature.
引用
收藏
页码:10951 / 10953
页数:3
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