Dietary docosahexaenoic acid as a source of eicosapentaenoic acid in vegetarians and omnivores

被引：106

作者：

Conquer, JA ^{[1
]}

Holub, BJ ^{[1
]}

机构：

[1] UNIV GUELPH,DEPT HUMAN BIOL & NUTR SCI,GUELPH,ON N1G 2W1,CANADA

来源：

LIPIDS | 1997年 / 32卷 / 03期

关键词：

D O I：

10.1007/s11745-997-0043-y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The utilization of dietary docosahexaenoic acid (DHA; 22:6n-3) as a source of eicosapentaenoic acid (EPA; 20,5n-3) via retroconversion was investigated in both vegetarians and omnivores. For this purpose, an EPA-free preparation of DHA was given as a daily supplement (1.62 g DHA) over a period of 6 wk. The dietary supplement provided for a marked increase in DHA levels in both serum phospholipid (from 2.1 to 7.1 mol% in vegetarians and 2.2 to 7.6 mol% in omnivores) and platelet phospholipid (from 1.1 to 3.4 mol% in vegetarians and 1.4 to 3.9 mol% in omnivores). EPA levels rose to a significant but much lesser extent, while 20:4n-6, 22:5n-6, and 22:5n-3 all decreased. Based on the serum phospholipid data, the retroconversion of DHA to EPA in vivo was estimated to be 9.4% overall with no significant difference between omnivores and vegetarians.

引用

页码：341 / 345

页数：5

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