hnRNP complexes: composition, structure, and function

被引：718

作者：

Krecic, AM

Swanson, MS

机构：

[1] Northwestern Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Chicago, IL 60611 USA

[2] Univ Florida, Coll Med, Dept Mol Genet & Microbiol, Gainesville, FL 32610 USA

[3] Univ Florida, Coll Med, Ctr Gene Therapy, Gainesville, FL 32610 USA

[4] Univ Florida, Coll Med, Ctr Mammalian Genet, Gainesville, FL 32610 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 1999年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0955-0674(99)80051-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are predominantly nuclear RNA-binding proteins that form complexes with RNA polymerase II transcripts. These proteins function in a staggering array of cellular activities, ranging from transcription and pre-mRNA processing in the nucleus to cytoplasmic mRNA translation and turnover. Recent studies suggest that several fundamental characteristics of hnRNPs account for their involvement in multiple regulatory pathways.

引用

页码：363 / 371

页数：9

共 62 条

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