Cucurbit[n]urils: from mechanism to structure and function

被引：382

作者：

Isaacs, Lyle ^{[1
]}

机构：

[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 06期

关键词：

HOST-GUEST COMPLEXATION; GLYCOLURIL DIMERS; DIASTEREOSELECTIVE FORMATION; CUCURBITURIL HOMOLOGS; MOLECULAR CLIPS; PK(A) SHIFTS; BINDING; STABILIZATION; ENCAPSULATION; RECOGNITION;

D O I：

10.1039/b814897j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This feature article details some of the unusual recognition properties of the cucurbit[n]uril family (CB[n]) of molecular containers. It discusses the mechanism of CB[ n] formation, which proceeds from glycoluril via methylene bridged glycoluril oligomers, along with descriptions of the structures and recognition properties of some kinetically stable macrocyclic intermediates along the way. These partially formed CB[n]-type receptors known as nor-seco-CB[n] display intriguing properties such as chiral recognition, homotropic allostery, and function as aldehyde reaction cucurbituril synthons.

引用

页码：619 / 629

页数：11

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