Transmission of a Y chromosomal deletion involving the deleted in azoospermia (DAZ) and chromodomain (CDY1) genes from father to son through intracytoplasmic sperm injection

被引：64

作者：

Kamischke, A

Gromoll, J

Simoni, M

Behre, HM

Nieschlag, E

机构：

[1] Univ Munster, Inst Reprod Med, D-48129 Munster, Germany

[2] Univ Munster, Dept Obstet & Gynaecol, D-48129 Munster, Germany

来源：

HUMAN REPRODUCTION | 1999年 / 14卷 / 09期

关键词：

DAZ; CDYa; ICSI; microdeletions; Y chromosome;

D O I：

10.1093/humrep/14.9.2320

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The transmission of a deleted in azoospermia (DAZ) deletion from a severely oligozoospermic patient to his son following intracytoplasmic sperm injection (ICSI) treatment is reported. The case report highlights the fertilizing capacity of spermatozoa carrying Y chromosome deletions in patients treated with ICSI and stresses the importance of genetic counselling in severe male infertility.

引用

页码：2320 / 2322

页数：3

共 20 条

[1] On the origin and frequency of Y chromosome deletions responsible for severe male infertility [J].