Validation of the Face Name Associative Memory Exam in cognitively normal older individuals

被引:57
作者
Amariglio, Rebecca E. [1 ,2 ,3 ]
Frishe, Katherine [1 ]
Olson, Lauren E. [1 ,2 ]
Wadsworth, Lauren P. [2 ]
Lorius, Natacha [1 ,2 ]
Sperling, Reisa A. [1 ,2 ,3 ]
Rentz, Dorene M. [1 ,2 ,3 ]
机构
[1] Brigham & Womens Hosp, Ctr Alzheimer Res & Treatment, Dept Neurol, Boston, MA 02115 USA
[2] Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02114 USA
[3] Harvard Univ, Sch Med, Boston, MA USA
关键词
Preclinical Alzheimer's disease; Aging; Neuropsychology; Instrument validation; PRECLINICAL ALZHEIMERS-DISEASE; AMYLOID DEPOSITION; IMPAIRMENT; DEMENTIA; PERFORMANCE; DEFICITS; FMRI;
D O I
10.1080/13803395.2012.666230
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
The recently developed Face Name Associative Memory Exam (FNAME), a challenging paired associative learning task, shows promise in detecting the subtle cognitive changes characteristic of preclinical Alzheimer's disease. In this study, we evaluated the validity and reliability of the FNAME in 210 cognitively normal older individuals (58-90 years of age). Construct validity of the measure was assessed by principal components analysis, which revealed two independent factors. Correlations between the FNAME subtests and another episodic memory test were significant. The results indicated strong test-retest reliability in a subsample (n = 41). Normative data stratified by age were also generated.
引用
收藏
页码:580 / 587
页数:8
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