Thyroid cancer

被引：1601

作者：

Cabanillas, Maria E. ^{[1
]}

McFadden, David G. ^{[2
]}

Durante, Cosimo ^{[3
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Div Internal Med, Dept Endocrine Neoplasia & Hormonal Disorders, Houston, TX 77230 USA

[2] Univ Texas Southwestern Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA

[3] Sapienza Univ Rome, Dept Internal Med & Med Specialties, Rome, Italy

来源：

LANCET | 2016年 / 388卷 / 10061期

关键词：

TERT PROMOTER MUTATIONS; BRAF V600E MUTATION; RADIOIODINE REMNANT ABLATION; FOLLOW-UP; ASSOCIATION GUIDELINES; SERUM THYROGLOBULIN; PHOSPHATIDYLINOSITOL; 3-KINASE/AKT; BRAF(V600E) MUTATION; DOUBLE-BLIND; PHASE-II;

D O I：

10.1016/S0140-6736(16)30172-6

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Thyroid cancer is the fifth most common cancer in women in the USA, and an estimated over 62 000 new cases occurred in men and women in 2015. The incidence continues to rise worldwide. Differentiated thyroid cancer is the most frequent subtype of thyroid cancer and in most patients the standard treatment ( surgery followed by either radioactive iodine or observation) is effective. Patients with other, more rare subtypes of thyroid cancer-medullary and anaplastic-are ideally treated by physicians with experience managing these malignancies. Targeted treatments that are approved for differentiated and medullary thyroid cancers have prolonged progression-free survival, but these drugs are not curative and therefore are reserved for patients with progressive or symptomatic disease.

引用

页码：2783 / 2795

页数：13

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