Progesterone receptor expression in the brainstem of the female rat

被引：40

作者：

Kastrup, Y

Hallbeck, M

Amandusson, Å

Hirata, S

Hermanson, O

Blomqvist, A ^{[1
]}

机构：

[1] Linkoping Univ, Fac Hlth Sci, Div Cell Biol, S-58185 Linkoping, Sweden

[2] Yamanaski Med Coll, Dept Obstet & Gynecol, Yamanashi 4093898, Japan

来源：

NEUROSCIENCE LETTERS | 1999年 / 275卷 / 02期

关键词：

progesterone receptor; in situ hybridization; immunohistochemistry; brainstem; spinal cord; autonomic regulation; pain modulation; rat;

D O I：

10.1016/S0304-3940(99)00753-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

By using in situ hybridization and immunohistochemistry, the presence of neurons expressing progesterone receptor mRNA (PR mRNA) and progesterone receptor-like immunoreactivity (PR-LI) was examined in the brainstem and spinal cord of female rats. Neurons expressing PR mRNA and PR-LI were seen in the ventrolateral medulla, the parvocellular reticular formation and the nucleus of the solitary tract. PR mRNA, but not PR-LI, was seen in the hypoglossal nucleus, the inferior olive, the locus coeruleus and the pa rabrachial nucleus. No consistent la bell ng was present in the spina I cord. These findings show that progesterone receptors are expressed in brainstem areas involved in various functions, including autonomic regulation and pain modulation. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：85 / 88

页数：4

共 19 条

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