HiTC: exploration of high-throughput 'C' experiments

被引：142

作者：

Servant, Nicolas ^{[1
,2
,3
]}

Lajoie, Bryan R. ^{[4
]}

Nora, Elphege P. ^{[1
,5
,6
]}

Giorgetti, Luca ^{[1
,5
,6
]}

Chen, Chong-Jian ^{[1
,2
,3
,5
,6
]}

Heard, Edith ^{[1
,5
,6
]}

Dekker, Job ^{[4
]}

Barillot, Emmanuel ^{[1
,2
,3
]}

机构：

[1] Inst Curie, F-75248 Paris, France

[2] INSERM, U900, F-75248 Paris, France

[3] Ecole Mines ParisTech, F-77300 Fontainebleau, France

[4] Univ Massachusetts, Sch Med, Dept Biochem & Mol Pharmacol, Worcester, MA 01605 USA

[5] CNRS, UMR3215, F-75248 Paris, France

[6] INSERM, U934, F-75248 Paris, France

来源：

BIOINFORMATICS | 2012年 / 28卷 / 21期

关键词：

CHROMOSOME CONFORMATION CAPTURE; NUCLEAR-ORGANIZATION; DOMAINS; GENOME;

D O I：

10.1093/bioinformatics/bts521

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

The R/Bioconductor package HiTC facilitates the exploration of high-throughput 3C-based data. It allows users to import and export 'C' data, to transform, normalize, annotate and visualize interaction maps. The package operates within the Bioconductor framework and thus offers new opportunities for future development in this field.

引用

页码：2843 / 2844

页数：2

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