The reaction of spiroepoxycyclohexadienones towards cyanide nucleophiles

被引：6

作者：

Córdoba, R

Csáky, AG

Plumet, J

Ortiz, FL

Herrera, R

Jiménez-Vázquez, HA

Tamariz, J

机构：

[1] Univ Complutense, Fac Quim, Dept Quim Organ, E-28040 Madrid, Spain

[2] Univ Almeria, Area Quim Organ, Almeria 04120, Spain

[3] Univ Michoacana, Inst Invest Quim Biol, Morelia 58066, Michoacan, Mexico

[4] Inst Politecn Nacl, Excuela Nacl Ciencias Biol, Mexico City, DF, Mexico

来源：

TETRAHEDRON | 2004年 / 60卷 / 17期

关键词：

epoxides; catalysis; cyanides;

D O I：

10.1016/j.tet.2004.03.007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of spiroepoxycyclohexadienones 1 with TMSCN in the presence of catalytic amounts of Bu4NCN results in the formation of two diastereomeric cyanohydrins. Alternatively, the reaction of I with equimolecular amounts of Bu4NCN gave rise to products arising from two other different reaction paths. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：3825 / 3830

页数：6

共 16 条

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[2]

2-R

[3]

ARENZ C, 2001, EUR J ORG CHEM JAN, P137

[4] Diels-Alder reaction of 4-bromo-6-spiroepoxycyclohexa-2,4-dienone with electron-rich and neutral dienophiles. [J].