Cerebellar vermis lobules VIII-X in autism

被引：74

作者：

Levitt, JG

Blanton, R

Capetillo-Cunliffe, L

Guthrie, D

Toga, A

McCracken, JT

机构：

[1] Univ Calif Los Angeles, Dept Psychiat, Los Angeles, CA USA

[2] Univ Calif Los Angeles, Lab Neuroimaging, Los Angeles, CA USA

[3] Univ Calif Los Angeles, Inst Neuropsychiat, Los Angeles, CA 90024 USA

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 1999年 / 23卷 / 04期

关键词：

autism; cerebellum; IQ; MRI; vermis;

D O I：

10.1016/S0278-5846(99)00021-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

1. The aim was to investigate cerebellar vermis cross-sectional area in a group of high-functioning autistic children and normal control children. 2. Cerebellar vermis area measurements were completed on MRI scans from 8 autistic children (mean age 12.5 +/- 2.2, mean IQ 83.3 +/- 11.9) and 21 normal children (mean age 12.0 +/- 2.8, mean IQ 115 +/- 11). 3. The area of cerebellar vermis lobules Vm-X was significantly smaller in the autistic children than in the normal control subjects. ANCOVA demonstrated a confounding effect of IQ on these results. 4. Larger studies of autistic and normal subjects will be needed to assess the relationship between cerebellar abnormalities, autistic symptoms and IQ.

引用

页码：625 / 633

页数：9

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