Cardiovascular Drugs in Pregnancy

被引：25

作者：

Frishman, William H. ^{[1
]}

Elkayam, Uri ^{[2
]}

Aronow, Wilbert S. ^{[1
]}

机构：

[1] New York Med Coll, Westchester Med Ctr, Dept Med, Div Cardiol, Valhalla, NY 10595 USA

[2] USC Sch Med, Dept Med, Los Angeles, CA 90033 USA

来源：

CARDIOLOGY CLINICS | 2012年 / 30卷 / 03期

关键词：

Pregnancy; Gestation; Teratogenic fetal risk; Pharmacotoxicity; Adverse reactions; FETAL SUPRAVENTRICULAR TACHYCARDIA; CONVERTING-ENZYME-INHIBITOR; MOLECULAR-WEIGHT HEPARIN; SODIUM-NITROPRUSSIDE; AMIODARONE TREATMENT; PLASMINOGEN-ACTIVATOR; SUBCUTANEOUS HEPARIN; HEMODYNAMIC-CHANGES; PULMONARY-EMBOLISM; ATRIAL-FLUTTER;

D O I：

10.1016/j.ccl.2012.04.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiovascular drugs are used in pregnancy to treat maternal and fetal conditions. Mothers may also require drug therapy postpartum. Most cardiovascular drugs taken by pregnant women can cross the placenta and therefore expose the developing embryo and fetus to their pharmacologic and teratogenic effects. These effects are influenced by the intrinsic pharmacokinetic properties of a given drug and by the complex physiologic changes occurring during pregnancy. Many drugs are also transferred into human milk with potential adverse effects on the nursing infant. This article summarizes some of the literature concerning the risks and benefits of using cardiovascular drugs during pregnancy.

引用

页码：463 / +

页数：30

共 166 条

[1]

AcGehee W., 1998, CARDIAC PROBLEMS PRE, P407

[2]

ALLAN LD, 1991, BRIT HEART J, V65, P46

[3] PLACENTAL TRANSPORT OF LOW-MOLECULAR WEIGHT HEPARIN IN THE PREGNANT SHEEP [J].

ANDREW, M ;

BONEU, B ;

CADE, J ;

CERSKUS, AL ;

HIRSH, J ;

JEFFERIES, A ;

TOWELL, ME ;

BUCHANAN, MR .

BRITISH JOURNAL OF HAEMATOLOGY, 1985, 59 (01) :103-108

[4]

[Anonymous], 1996, DRUG INF HLTH CAR PR, V1

[5]

Awad K, 2000, Heart Dis, V2, P124

[6] EMERGENCY TREATMENT WITH RECOMBINANT TISSUE PLASMINOGEN-ACTIVATOR OF PULMONARY-EMBOLISM IN A PREGNANT WOMAN WITH ANTITHROMBIN-III DEFICIENCY [J].

BAUDO, F ;

CAIMI, TM ;

REDAELLI, R ;

NOSARI, AM ;

MAURI, M ;

LEONARDI, G ;

DECATALDO, F .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1990, 163 (04) :1274-1275

[7] THE EFFECT OF ACUTE VOLUME EXPANSION AND VASODILATATION WITH VERAPAMIL ON UTERINE AND UMBILICAL ARTERY DOPPLER INDEXES IN SEVERE PREECLAMPSIA [J].

BELFORT, M ;

AKOVIC, K ;

ANTHONY, J ;

SAADE, G ;

KIRSHON, B ;

MOISE, K .

JOURNAL OF CLINICAL ULTRASOUND, 1994, 22 (05) :317-325

[8]

BELFORT MA, 1990, OBSTET GYNECOL, V75, P970

[9]

BEROYZ G, 1994, LANCET, V343, P619

[10] PLACENTAL-TRANSFER OF LIDOCAINE - EFFECTS OF FETAL ACIDOSIS [J].

BIEHL, D ;

SHNIDER, SM ;

LEVINSON, G ;

CALLENDER, K .

ANESTHESIOLOGY, 1978, 48 (06) :409-412

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