Fibre-optic interferometric immuno-sensor using long period grating

被引：53

作者：

Kim, DW ^{[1
]}

Zhang, Y ^{[1
]}

Cooper, KL ^{[1
]}

Wang, A ^{[1
]}

机构：

[1] Virginia Polytech Inst & State Univ, Bradley Dept Elect & Comp Engn, Ctr Photon Technol, Blacksburg, VA 24061 USA

来源：

ELECTRONICS LETTERS | 2006年 / 42卷 / 06期

关键词：

D O I：

10.1049/el:20060040

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A species-specific biosensor is presented based on the combined use of a reflection mode long period fibre grating with nanoscale self-assembly. Self-assembled polyelectrolyte layers and the immobilisation of immunoglobulin G (IgG) were used for sensor fabrication. The sensor's fringe position shift induced by specific antigen-antibody binding has been observed, and non-specific binding was minimised with binding block. The results show the feasibility of the sensor for various bio/chemical applications.

引用

页码：324 / 325

页数：2

共 7 条

[1] ADSORPTION OF MONOCLONAL IGGS AND THEIR F(AB')(2) FRAGMENTS ONTO POLYMERIC SURFACES [J].