Substantia nigra echogenicity is normal in non-extrapyramidal cerebral disorders but increased in Parkinson's disease

被引：154

作者：

Walter, U ^{[1
]}

Wittstock, M ^{[1
]}

Benecke, R ^{[1
]}

Dressler, D ^{[1
]}

机构：

[1] Univ Rostock, Dept Neurol, D-18147 Rostock, Germany

来源：

JOURNAL OF NEURAL TRANSMISSION | 2002年 / 109卷 / 02期

关键词：

transcranial sonography; Parkinson's disease; substantia nigra hyperechogenicity;

D O I：

10.1007/s007020200015

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Transcranial sonography (TCS) revealed substantia nigra (SN) hyperechogenicity in idiopathic Parkinson's disease (IPD). To further evaluate specificity of this finding, we examined 30 IPD patients and 30 age-matched subjects with non-extrapyramidal cerebral disorders (NED). All IPD patients showed a SN hyperechogenicity, in 17 it was bilateral and in 13 unilateral. 7 NED patients had a SN hyperechogenicity, in all it was unilateral, confirming previous results in healthy subjects. Bilateral SN hyperechogenicity indicates IPD and normal SN echogenicity indicates NED. In 30% of patients TCS does not distinguish between lPD and NED. Data further support the assumption that bilateral SN hyperechogenicity is specific for IPD.

引用

页码：191 / 196

页数：6

共 5 条

[1] DEGENERATION OF SUBSTANTIA-NIGRA IN CHRONIC PARKINSONS-DISEASE VISUALIZED BY TRANSCRANIAL COLOR-CODED REAL-TIME SONOGRAPHY [J].