Co-electropolymerization of a viologen oligomer and lipoamide dehydrogenase on an electrode surface. Application to cofactor regeneration

被引：8

作者：

Leonida, MD ^{[1
]}

Fry, AJ ^{[1
]}

Sobolov, SB ^{[1
]}

Voivodov, KI ^{[1
]}

机构：

[1] WESLEYAN UNIV,HALL ATWATER LAB CHEM,MIDDLETOWN,CT 06459

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 14期

关键词：

D O I：

10.1016/0960-894X(96)00298-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We report here a novel enzyme electrode obtained by electrochemically copolymerization of a redox enzyme with an oligomeric organic redox mediator on the surface of a glassy carbon electrode. This electrode serves as an efficient catalyst for the regeneration of the cofactor in enzymatic syntheses requiring NADH. The reaction shows a relatively short induction period and the rate of product formation is higher than for similar electrodes upon which the enzyme and redox mediator are physically trapped under a Nafion membrane. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：1663 / 1666

页数：4

共 15 条

[1]

ALMEIDA NF, 1991, BIOTECHNOLOGY : BRIDGING RESEARCH AND APPLICATIONS, P89

[2]

ALMEIDA NF, 1992, THESIS U PITTSBURGH

[3] THERMODYNAMIC ASPECTS OF REDOX REACTIONS ON ELECTRODES COATED WITH THIN, ION EXCHANGING POLYMER-FILMS [J].

BRAUN, H ;

STORCK, W ;

DOBLHOFER, K .

JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 1983, 130 (04) :807-811

[4] A NOVEL POLYVIOLOGEN ELECTRODE FABRICATED BY ELECTROCHEMICAL CROSS-LINKING [J].

CHANG, HC ;

OSAWA, M ;

MATSUE, T ;

UCHIDA, I .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (09) :611-612

[5] CATALYSIS OF 1,2-DIBROMO-1,2-DIPHENYLETHANE REDUCTION ON PLATINUM AND CARBON FELT ELECTRODES COATED BY POLYPYRROLE FILMS CONTAINING 4,4'-BIPYRIDINIUM GROUPS - EFFECTS OF FILM THICKNESS, FILM COMPOSITION AND COMPARISON WITH HOMOGENEOUS CATALYSIS [J].

COCHE, L ;

MOUTET, JC .

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1987, 224 (1-2) :111-122

[6]

DIAZ A, 1985, J ELECTROCHEM SOC, V132, P837

[7] POLYVIOLOGENS - NOVEL CLASS OF CATIONIC POLYELECTROLYTE REDOX POLYMERS [J].

FACTOR, A ;

HEINSOHN, GE .

JOURNAL OF POLYMER SCIENCE PART B-POLYMER LETTERS, 1971, 9 (04) :289-&

[8] ELECTROENZYMATIC SYNTHESIS (REGENERATION OF NADH COENZYME) - USE OF NAFION ION-EXCHANGE FILMS FOR IMMOBILIZATION OF ENZYME AND REDOX MEDIATOR [J].

FRY, AJ ;

SOBOLOV, SB ;

LEONIDA, MD ;

VOIVODOV, KI .

TETRAHEDRON LETTERS, 1994, 35 (31) :5607-5610

[9]

FRY AJ, 1994, B ELECTROCHEM SOC JA, V62, P1260

[10] DYE LOADED POLYMER ELECTRODES .3. GENERATION OF PHOTOGALVANIC EFFECTS AT N-SNO2 ELECTRODES COATED WITH POLY(4-VINYL PYRIDINE) FILMS CONTAINING ROSE-BENGAL [J].

KAMAT, PV ;

FOX, MA .

JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 1984, 131 (05) :1032-1037

← 1 2 →