Prevalence and predictors of depressive, anxiety and substance use disorders in HIV-infected and uninfected men: A longitudinal evaluation

被引:128
作者
Dew, MA
Becker, JT
Sanchez, J
Caldararo, R
Lopez, OL
Wess, J
Dorst, SK
Banks, G
机构
[1] UNIV PITTSBURGH,SCH MED,DEPT PSYCHOL,PITTSBURGH,PA 15213
[2] UNIV PITTSBURGH,SCH MED,DEPT EPIDEMIOL,PITTSBURGH,PA 15213
[3] UNIV PITTSBURGH,SCH MED,DEPT NEUROL,PITTSBURGH,PA 15213
[4] UNIV PITTSBURGH,SCH MED,DEPT FAMILY MED & CLIN EPIDEMIOL,PITTSBURGH,PA 15213
[5] UNIV PITTSBURGH,MED CTR,PITTSBURGH,PA 15213
关键词
D O I
10.1017/S0033291796004552
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Background. There is little agreement on whether the prevalence of psychiatric disorder is elevated in HIV-seropositive (HIV +) populations compared with uninfected persons. However, evaluation of this issue has been limited by difficulties of sampling, study design and failure to control for other risk factors for disorder. Methods.Prevalence and clinical characteristics of DSM-III-R major depressive disorder generalized anxiety disorder, adjustment disorder, and alcohol and substance abuse/dependence were evaluated in a representative sample of HIV+ men attending primary care physicians' offices in a defined geographical area. Lifetime prevalence at baseline and 1-year rates during longitudinal follow-up were determined for the 113 HIV+ men, as well as 57 HIV- men, via standardized interview. Multivariate analyses considered unique and combined effects of HIV serostatus and other risk factors on likelihood of disorder. Results. Although there were no differences in lifetime rates prior to baseline, HIVS men were at greater risk for disorders during the prospective study period. For MDD, this effect was maintained even after controlling for other risk factors. Several of these other factors bore their own effects: regardless of HIV serostatus, men were susceptible to psychopathology if at baseline they were younger, had a lifetime psychiatric history, or had poor social supports or a low sense of personal mastery. Conclusions. The risk of certain psychiatric disorders appears uniquely elevated in HIVS men. Since other factors also influence risk, interventions designed to minimize psychopathology during HIV infection should attend to both HIV-related and non-HIV-related risk factors.
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页码:395 / 409
页数:15
相关论文
共 72 条
[1]  
ALLOWAY R, 1987, PSYCHOL MED, V17, P81
[2]  
[Anonymous], 1987, DIAGNOSTIC STAT MANU, V4th
[3]  
ATKINSON JH, 1994, PSYCHIAT CLIN N AM, V17, P17
[4]  
ATKINSON JH, 1988, ARCH GEN PSYCHIAT, V45, P859
[5]  
Billings A G, 1981, J Behav Med, V4, P139, DOI 10.1007/BF00844267
[6]  
Bix B C, 1995, J Int Neuropsychol Soc, V1, P581
[7]   PREVALENCE OF PSYCHIATRIC-DISORDERS IN EARLY STAGES OF HIV-INFECTION [J].
BROWN, GR ;
RUNDELL, JR ;
MCMANIS, SE ;
KENDALL, SN ;
ZACHARY, R ;
TEMOSHOK, L .
PSYCHOSOMATIC MEDICINE, 1992, 54 (05) :588-601
[8]   Psychological distress among caregivers to heart transplant recipients [J].
Canning, RD ;
Dew, MA ;
Davidson, S .
SOCIAL SCIENCE & MEDICINE, 1996, 42 (04) :599-608
[9]   THE PSYCHOSOCIAL IMPACT OF HIV-INFECTION IN GAY MEN - A CONTROLLED INVESTIGATION AND FACTORS ASSOCIATED WITH PSYCHIATRIC MORBIDITY [J].
CATALAN, J ;
KLIMES, I ;
DAY, A ;
GARROD, A ;
BOND, A ;
GALLWEY, J .
BRITISH JOURNAL OF PSYCHIATRY, 1992, 161 :774-778
[10]   THE PSYCHOSOCIAL IMPACT OF HIV-INFECTION IN MEN WITH HEMOPHILIA - CONTROLLED INVESTIGATION AND FACTORS ASSOCIATED WITH PSYCHIATRIC MORBIDITY [J].
CATALAN, J ;
KLIMES, I ;
BOND, A ;
DAY, A ;
GARROD, A ;
RIZZA, C .
JOURNAL OF PSYCHOSOMATIC RESEARCH, 1992, 36 (05) :409-416