Cadmium exposure in pregnancy and lactation in relation to iron status

被引:197
作者
Åkesson, A
Berglund, M
Schütz, A
Bjellerup, P
Bremme, K
Vahter, M
机构
[1] Karolinska Inst, Inst Environm Med, Div Met & Hlth, S-17177 Stockholm, Sweden
[2] Univ Lund Hosp, Dept Occupat & Environm Med, S-22185 Lund, Sweden
[3] Karolinska Hosp, Dept Clin Chem, S-10401 Stockholm, Sweden
[4] Karolinska Hosp, Dept Woman & Child Hlth, S-10401 Stockholm, Sweden
关键词
D O I
10.2105/AJPH.92.2.284
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 [公共卫生与预防医学]; 120402 [社会医学与卫生事业管理];
摘要
Objectives. The purpose of this study was to determine the impact of iron status on cadmium dose among pregnant women. Methods. Iron status and cadmium concentration in blood, urine, and placenta were determined among women followed for 2 years from early pregnancy. Results. Blood cadmium and urinary cadmium were correlated with iron status throughout the study period. Urinary cadmium increased longitudinally among women with exhausted iron stores during their pregnancy. The increase in urinary cadmium with age was more pronounced in multiparous than in nulliparous women. Conclusions. Iron deficiency during pregnancy leads to increased cadmium absorption and body burden. Multiparous women exhibit additional increases with increasing age.
引用
收藏
页码:284 / 287
页数:4
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