A new Smurf in the village

被引:38
作者
Arora, K [1 ]
Warrior, R
机构
[1] Univ Calif Irvine, Dept Dev & Cell Biol, Irvine, CA 92697 USA
[2] Univ So Calif, Program Mol Biol, Los Angeles, CA 90089 USA
关键词
D O I
10.1016/S1534-5807(01)00067-3
中图分类号
Q2 [细胞生物学];
学科分类号
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要
TGF-beta signaling is modulated by Smurfs, E3-ubiquitin ligases that selectively target the receptors and Smad proteins for degradation. New evidence from Drosophila suggests that Smurfs regulate the amplitude and the duration of the cellular response to signaling in vivo.
引用
收藏
页码:441 / 442
页数:2
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