TGF-beta signaling is modulated by Smurfs, E3-ubiquitin ligases that selectively target the receptors and Smad proteins for degradation. New evidence from Drosophila suggests that Smurfs regulate the amplitude and the duration of the cellular response to signaling in vivo.
机构:
Technion Israel Inst Technol, Fac Med, Biochem Unit, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Fac Med, Biochem Unit, IL-31096 Haifa, Israel
Hershko, A
;
Ciechanover, A
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机构:Technion Israel Inst Technol, Fac Med, Biochem Unit, IL-31096 Haifa, Israel
机构:
Technion Israel Inst Technol, Fac Med, Biochem Unit, IL-31096 Haifa, IsraelTechnion Israel Inst Technol, Fac Med, Biochem Unit, IL-31096 Haifa, Israel
Hershko, A
;
Ciechanover, A
论文数: 0引用数: 0
h-index: 0
机构:Technion Israel Inst Technol, Fac Med, Biochem Unit, IL-31096 Haifa, Israel