Immunogold cytochemistry in neuroscience

被引:44
作者
Amiry-Moghaddam, Mahmood [1 ]
Ottersen, Ole Petter [1 ]
机构
[1] Univ Oslo, Inst Basic Med Sci, Lab Mol Neurosci, Oslo, Norway
关键词
POSTSYNAPTIC DENSITY; ELECTRON-MICROSCOPE; NMDA RECEPTORS; RAT CEREBELLUM; AMPA RECEPTORS; GLUTAMATE; IMMUNOCYTOCHEMISTRY; SYNAPSES; ANTIBODY; BRAIN;
D O I
10.1038/nn.3418
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The complexity of the central nervous system calls for immunocytochemical procedures that allow target proteins to be localized with high precision and with opportunities for quantitation. Immunogold procedures stand out as particularly powerful in this regard. Although these procedures have found wide application in the neuroscience community, they present limitations and pitfalls that must be taken into account. At the same time, these procedures offer potentials that remain to be fully realized.
引用
收藏
页码:798 / 804
页数:7
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