Neurosensory mechanotransduction

被引：304

作者：

Chalfie, Martin ^{[1
]}

机构：

[1] Columbia Univ, Dept Biol Sci, New York, NY 10027 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2009年 / 10卷 / 01期

关键词：

TOUCH RECEPTOR NEURONS; VERTEBRATE HAIR-CELLS; CAENORHABDITIS-ELEGANS; C-ELEGANS; MECHANOSENSORY TRANSDUCTION; TIP-LINK; ESCHERICHIA-COLI; TRP CHANNELS; ION CHANNELS; SENSORY MECHANOTRANSDUCTION;

D O I：

10.1038/nrm2595

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Neurons that sense touch, sound and acceleration respond rapidly to specific mechanical signals. The proteins that transduce these signals and underlie these senses, however, are mostly unknown. Research over the past decade has suggested that members of three families of channel proteins are candidate transduction molecules. Current studies are directed towards characterizing these candidates, determining how they are mechanically gated and discovering new molecules that are involved in mechanical sensing.

引用

页码：44 / 52

页数：9

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