Enantiopure oxazolidinones as chiral acids in the asymmetric protonation of N-Boc pyrrole derived enolates

被引：17

作者：

Carbery, DR ^{[1
]}

Donohoe, TJ ^{[1
]}

机构：

[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 06期

关键词：

D O I：

10.1039/b316719d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The first use of geminally disubstituted oxazolidinones as chiral protonating agents is described: these new acids are able to directly protonate an enolate generated by the ammonia free partial reduction of an electron deficient pyrrole and give up to 68% ee in the pyrroline product.

引用

页码：722 / 723

页数：2

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