The nutritional modulation of the evolving intestine

被引：30

作者：

Canani, Roberto Berni ^{[1
]}

Passariello, Annalisa ^{[1
]}

Buccigrossi, Vittoria ^{[1
]}

Terrin, Gianluca ^{[1
]}

Guarino, Alfredo ^{[1
]}

机构：

[1] Univ Naples Federico II, Dept Pediat, I-80131 Naples, Italy

来源：

JOURNAL OF CLINICAL GASTROENTEROLOGY | 2008年 / 42卷 / 08期

关键词：

newborn; human milk; microflora; mucosal immunity; epigenetics;

D O I：

10.1097/MCG.0b013e31817da155

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Nutrition plays a major role in the modulation of the evolving human gut influencing all the main components of the intestinal ecosystem. The regulatory role of nutrition is particularly crucial in the early postnatal period but it continues also in subsequent ages when the development of the gastrointestinal tract is completed. Recent data support the hypothesis that nutrition can affect some inherited disorders of gastrointestinal tract. These "epigenetic" mechanisms are involved in the development of intestinal enzymes, hormones, transporters, and immunity. This is an expanding research area related to the possible nutritional intervention in selected clinical condition. This paper is focused on the main components and mechanisms of action of the nutritional modulation on intestinal development.

引用

页码：S197 / S200

页数：4

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