Diabetes and dementia

被引:10
作者
Bahrmann, A. [1 ]
Bahrmann, P. [2 ,3 ]
Kubiak, T. [4 ]
Kopf, D. [5 ]
Oster, P. [6 ]
Sieber, C. C. [2 ,3 ]
Daniel, W. G. [1 ]
机构
[1] Univ Erlangen Nurnberg, Med Klin 2, D-91054 Erlangen, Germany
[2] Klinikum Nurnberg, Med Klin 2, Nurnberg, Germany
[3] Univ Erlangen Nurnberg, Lehrstuhl Innere Med Geriatr, Inst Biomed Alterns, D-91054 Erlangen, Germany
[4] Johannes Gutenberg Univ Mainz, Inst Psychol, Mainz, Germany
[5] Marien Hosp, Klin Geriatr, Hamburg, Germany
[6] Heidelberg Univ, Geriatr Zentrum Klinikum, AGAPLESION Bethanien Krankenhaus, D-6900 Heidelberg, Germany
来源
ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE | 2012年 / 45卷 / 01期
关键词
Diabetes mellitus; type; 2; Dementia; Cognition disorders; Hyperglycemia; Cytokines; COGNITIVE IMPAIRMENT; RISK-FACTORS; COMORBID DEPRESSION; ALZHEIMERS-DISEASE; OLDER PATIENTS; MELLITUS; PEOPLE; DECLINE; HEALTH; ASSOCIATION;
D O I
10.1007/s00391-011-0269-z
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
030301 [社会学]; 100201 [内科学];
摘要
Diabetes mellitus is a known risk factor for cognitive dysfunction and dementia. Chronic hyperglycemia, genetic predisposition, arterial hypertension, hyperlipoproteinemia, micro- and macrovascular diseases, and depression play a major role in the development of cognitive dysfunction. Both pathophysiology of diabetes and dementia and the specifics of diabetes therapy in patients with dementia are presented in this review.
引用
收藏
页码:17 / 22
页数:6
相关论文
共 45 条
[1]
The prevalence of comorbid depression in adults with diabetes - A meta-analysis [J].
Anderson, RJ ;
Freedland, KE ;
Clouse, RE ;
Lustman, PJ .
DIABETES CARE, 2001, 24 (06) :1069-1078
[2]
[Anonymous], DIABETOLOGIE
[3]
Diabetes mellitus and cognition: is there a link? [J].
Barrou, Zina ;
Lemaire, Aurelie ;
Boddaert, Jacques ;
Verny, Marc .
PSYCHOLOGIE & NEUROPSYCHIATRIE DU VIEILLISSEMENT, 2008, 6 (03) :189-198
[4]
Depression predicts increased incidence of adverse health outcomes in older Mexican Americans with type 2 diabetes [J].
Black, SA ;
Markides, KS ;
Ray, LA .
DIABETES CARE, 2003, 26 (10) :2822-2828
[5]
Structured treatment and teaching of patients with Type 2 diabetes mellitus and impaired cognitive function - the DICOF trial [J].
Braun, A ;
Muller, UA ;
Muller, R ;
Leppert, K ;
Schiel, R .
DIABETIC MEDICINE, 2004, 21 (09) :999-1006
[6]
Severe hypoglycaemia and cognitive impairment in older patients with diabetes: the Fremantle Diabetes Study [J].
Bruce, D. G. ;
Davis, W. A. ;
Casey, G. P. ;
Clarnette, R. M. ;
Brown, S. G. A. ;
Jacobs, I. G. ;
Almeida, O. P. ;
Davis, T. M. E. .
DIABETOLOGIA, 2009, 52 (09) :1808-1815
[7]
Midlife cardiovascular risk factors and brain morphology in identical older male twins [J].
Carmelli, D ;
Swan, GE ;
Reed, T ;
Wolf, PA ;
Miller, BL ;
DeCarli, C .
NEUROLOGY, 1999, 52 (06) :1119-1124
[8]
Survival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study [J].
Currie, Craig J. ;
Peters, John R. ;
Tynan, Aodan ;
Evans, Marc ;
Heine, Robert J. ;
Bracco, Oswaldo L. ;
Zagar, Tony ;
Poole, Chris D. .
LANCET, 2010, 375 (9713) :481-489
[9]
Diabetic Retinopathy and Cognitive Decline in Older People With Type 2 Diabetes The Edinburgh Type 2 Diabetes Study [J].
Ding, Jie ;
Strachan, Mark W. J. ;
Reynolds, Rebecca M. ;
Frier, Brian M. ;
Deary, Ian J. ;
Fowkes, F. Gerald R. ;
Lee, Amanda J. ;
McKnight, Janet ;
Halpin, Patricia ;
Swa, Ken ;
Price, Jackie F. .
DIABETES, 2010, 59 (11) :2883-2889
[10]
NIDDM and blood pressure as risk factors for poor cognitive performance - The Framingham Study [J].
Elias, PK ;
Elias, MF ;
DAgostino, RB ;
Cupples, LA ;
Wilson, PW ;
Silbershatz, H ;
Wolf, PA .
DIABETES CARE, 1997, 20 (09) :1388-1395