Stereocontrolled approaches to 2-(2-aminoalkyl)-1-hydroxycyclopropanes

被引：13

作者：

Baird, MS ^{[1
]}

Huber, FAM

Clegg, W

机构：

[1] Univ Coll N Wales, Dept Chem, Bangor LL57 2UW, Gwynedd, Wales

[2] Univ Newcastle Upon Tyne, Dept Chem, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

来源：

TETRAHEDRON | 2001年 / 57卷 / 49期

关键词：

isoxazolines; allyl alcohol; cyclopropenes; cyclopropanes;

D O I：

10.1016/S0040-4020(01)00996-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(1S,2S)-2[(S)-Amino(4-methoxyphenyl)methyl]cyclopropan-1-of together with a range of racemic 2-(2-aminoalkyl)-1-hydroxy-cyclopropanes were prepared by a stepwise procedure involving a 1,3-dipolar cycloaddition of a nitrile oxide to a cyclopropene followed by reduction of the derived bicycle. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：9849 / 9858

页数：10

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