Nomenclature of the human immunoglobulin lambda (IGL) genes

被引：33

作者：

Lefranc, MP ^{[1
]}

机构：

[1] Univ Montpellier 2, UPR CNRS 1142, LIGM,IMGT,Lab Immunogenet Mol, IGH,Nomenclature Comm, F-34396 Montpellier 5, France

来源：

EXPERIMENTAL AND CLINICAL IMMUNOGENETICS | 2001年 / 18卷 / 04期

关键词：

human; IMGT; immunoglobulin; lambda chain genes; orphons;

D O I：

10.1159/000049203

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

'Nomenclature of the Human Immunoglobulin Lambda (IGL) Genes', the 18th report of the 'IMGT Locus in Focus' section, provides the first complete list of all the human IGL genes. The total number of human IGL genes per haploid genome is 87-96 (93-102 if the orphons are included), of which 37-43 genes are functional. [IMGT/Human Genome Organization (HUGO) gene names and definitions of the human IGL genes on chromosome 22q 11.2 and IGL orphons on chromosomes 8 and 22 are provided with the gene functionality and the number of alleles, according to the rules of the IMGT Scientific chart, with the accession numbers of the IMGT reference sequences and with the accession ID of the Genome Database GDB and NCBI LocusLink databases, in which all the IMGT human IGL genes have been entered. The tables are available at the IMGT Marie-Paule page of IMGT, the international ImMunoGeneTies database (http:/firn9t.cines.fr) created by Marie-Paule Lefranc, Universit6 Montpellier II, CNRS, France.

引用

页码：242 / 254

页数：13

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